Electrosprayed core–shell microspheres for protein delivery

Electrosprayed core-shell microspheres for protein delivery.

This communication describes a single-step electrospraying technique that generates core-shell microspheres (CSMs) with encapsulated protein as the core and an amphiphilic biodegradable polymer as the shell. The protein release profiles of the electrosprayed CSMs showed steady release kinetics over 3 weeks without a significant initial burst.

2 Microspheres for Drug Delivery

Electrosprayed nanoparticles for drug delivery and pharmaceutical applications

Nanotechnology based Pharma has emerged significantly and has influenced the Pharma industry up to a considerable extent. Nanoparticles technology holds a good share of the nanotech Pharma and is significant in comparison with the other domains. Electrospraying technology answers the potential needs of nanoparticle production such as scalability, reproducibility, effective encapsulation etc. Ma...

Investigation on a novel core-coated microspheres protein delivery system.

Among the different approaches to achieve protein delivery, the use of polymers, specifically biodegraded, holds great promise. In this work, a new microsphere delivery system composed of alginate microcores surrounded by a biodegradable poly-DL-lactide-poly(ethylene glycol (PELA) was designed to improve the loading efficiency and stability of proteins. Alginate was solidified by calcium (MS-1)...

Bioadhesive Microspheres for Tuberculosis Drug Delivery

Tuberculosis (TB) is an infectious disease that mainly affects the lungs. For the treatment of tuberculosis, conventional drug delivery system fails to achieve efficient drug delivery system fails to achieve efficient drug delivery at the target site. Today, bioadhesive microspheres became a topic of great interest as a novel carrier for drug delivery. Bioadhesive microspheres offers longer ret...